L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Recombinant Protein | ADPPT recombinant protein
Recombinant Human L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]
Uniprot Description
AASDHPPT: Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN. Belongs to the P-Pant transferase superfamily. AcpS family.
Protein type: Amino Acid Metabolism - lysine biosynthesis; Amino Acid Metabolism - lysine degradation; EC 2.7.8.-; Transferase
Chromosomal Location of Human Ortholog: 11q22.3
Cellular Component: cytosol
Molecular Function: magnesium ion binding; phosphopantetheinyltransferase activity; protein binding
Biological Process: lysine biosynthetic process via aminoadipic acid; pantothenate metabolic process
Research Articles on ADPPT
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Product Notes
The ADPPT aasdhppt (Catalog #AAA9421393) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-309aa. The Recombinant Human L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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