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Rabbit anti-Human, Mouse QTRT2 Polyclonal Antibody | anti-QTRT2 antibody

QTRT2 Antibody

Gene Names
QTRT2; QTRTD1
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
QTRT2; Polyclonal Antibody; QTRT2 Antibody; FLJ12960; QTRD1_HUMAN; qtrtd1; queuine tRNA ribosyltransferase domain containing 1; Queuine tRNA-ribosyltransferase domain-containing protein 1; Queuine tRNA-ribosyltransferase subunit qtrtd1; anti-QTRT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
QTRT2 Antibody detects endogenous levels of QTRT2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-QTRT2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human QTRT2.
Conjugation
Unconjugated
Similarity
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
Subunit Structure
Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
Function
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4, 5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Note
May associate with the mitochondrion outer membrane.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,203 Da
NCBI Official Full Name
queuine tRNA-ribosyltransferase subunit QTRTD1 isoform 2
NCBI Official Synonym Full Names
queuine tRNA-ribosyltransferase accessory subunit 2
NCBI Official Symbol
QTRT2
NCBI Official Synonym Symbols
QTRTD1
NCBI Protein Information
queuine tRNA-ribosyltransferase subunit QTRTD1
UniProt Protein Name
Queuine tRNA-ribosyltransferase subunit QTRTD1
UniProt Gene Name
QTRTD1
UniProt Entry Name
QTRD1_HUMAN

Uniprot Description

QTRTD1: Interacts with QTRT1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily.

Protein type: EC 2.4.2.29

Chromosomal Location of Human Ortholog: 3q13.31

Cellular Component: cytoplasm; mitochondrial outer membrane; mitochondrion

Molecular Function: protein heterodimerization activity; protein homodimerization activity; queuine tRNA-ribosyltransferase activity

Biological Process: queuosine biosynthetic process; tRNA modification

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Product Notes

The QTRT2 qtrtd1 (Catalog #AAA9631135) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The QTRT2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's QTRT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the QTRT2 qtrtd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "QTRT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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