Rabbit DOCK10 Polyclonal Antibody | anti-DOCK10 antibody
DOCK10 Antibody
Gene Names
DOCK10; ZIZ3; DRIP2; Nbla10300
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DOCK10; Polyclonal Antibody; DOCK10 Antibody; 9330153B10Rik; A630054M16Rik; dedicator of cytokinesis 10; Dedicator of cytokinesis protein 10; DKFZp781A1532; DRIP2; Jr4; Jr5; KIAA0694; MGC183664; mKIAA0694; Nbla10300; R75174; ZIZ3; Zizimin 3; anti-DOCK10 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
DOCK10 Antibody detects endogenous levels of DOCK10.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-DOCK10 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human DOCK10.
Conjugation
Unconjugated
Similarity
The DHR-2 domain may mediate some GEF activity. Belongs to the DOCK family.
Tissue Specificity
Expressed at low level in brain and lung. Isoform 1 is enriched in normal T-cells, isoform 3 is enriched in normal B-cells and chronic lymphocytic leukemia (CLL) B-cells.
Function
Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP. Essential for dendritic spine morphogenesis in Purkinje cells and in hippocampal neurons, via a CDC42-mediated pathway. Sustains B-cell lymphopoiesis in secondary lymphoid tissues and regulates FCER2/CD23 expression.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-DOCK10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
249,531 Da
NCBI Official Full Name
dedicator of cytokinesis protein 10 DOCK10.2
NCBI Official Synonym Full Names
dedicator of cytokinesis 10
NCBI Official Symbol
DOCK10
NCBI Official Synonym Symbols
ZIZ3; DRIP2; Nbla10300
NCBI Protein Information
dedicator of cytokinesis protein 10; zizimin3; dopamine receptor interacting protein 2
UniProt Protein Name
Dedicator of cytokinesis protein 10
Protein Family
UniProt Gene Name
DOCK10
UniProt Synonym Gene Names
KIAA0694; ZIZ3
UniProt Entry Name
DOC10_HUMAN
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Product Notes
The DOCK10 dock10 (Catalog #AAA9631039) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DOCK10 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DOCK10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the DOCK10 dock10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOCK10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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