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Rabbit anti-Human, Mouse CDKL3 Polyclonal Antibody | anti-CDKL3 antibody

CDKL3 Antibody

Gene Names
CDKL3; NKIAMRE
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
CDKL3; Polyclonal Antibody; CDKL3 Antibody; CDKL3 protein; CDKL3_HUMAN; Cyclin dependent kinase like 3; Cyclin-dependent kinase-like 3; Serine/threonine-protein kinase NKIAMRE; anti-CDKL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
CDKL3 Antibody detects endogenous levels of CDKL3.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CDKL3 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human CDKL3.
Conjugation
Unconjugated
Similarity
The [NKR]KIAxRE motif seems to be a cyclin-binding region. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-CDKL3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,514 Da
NCBI Official Full Name
cyclin-dependent kinase-like 3 isoform 1
NCBI Official Synonym Full Names
cyclin-dependent kinase-like 3
NCBI Official Symbol
CDKL3
NCBI Official Synonym Symbols
NKIAMRE
NCBI Protein Information
cyclin-dependent kinase-like 3; serine-threonine protein kinase NKIAMRE; serine/threonine-protein kinase NKIAMRE
UniProt Protein Name
Cyclin-dependent kinase-like 3
Protein Family
UniProt Gene Name
CDKL3
UniProt Synonym Gene Names
NKIAMRE
UniProt Entry Name
CDKL3_HUMAN

NCBI Description

The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

CDKL3: a protein kinase of the CDKL family. Absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. The function of this gene has not yet been determined.

Protein type: Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); CMGC group; CDKL family

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: cytoplasm; nucleus

Molecular Function: cyclin-dependent protein kinase activity; ATP binding; protein kinase activity

Biological Process: regulation of cell cycle; protein modification process; positive regulation of dendrite morphogenesis; negative regulation of axon extension; protein amino acid phosphorylation

Research Articles on CDKL3

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Product Notes

The CDKL3 cdkl3 (Catalog #AAA9630844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDKL3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDKL3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the CDKL3 cdkl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDKL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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