Rabbit anti-Human, Mouse SGSM1 Polyclonal Antibody | anti-SGSM1 antibody
SGSM1 Antibody
Gene Names
SGSM1; RUTBC2
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SGSM1; Polyclonal Antibody; SGSM1 Antibody; KIAA1941; RUN and TBC1 domain containing 2; RUN and TBC1 domain containing protein 2; RUN and TBC1 domain-containing protein 2; RUTBC2; Sgsm1; SGSM1_HUMAN; Small G protein signaling modulator 1; Small G protein signaling modulator 1 protein; anti-SGSM1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SGSM1 Antibody detects endogenous levels of SGSM1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SGSM1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human SGSM1.
Conjugation
Unconjugated
Similarity
Belongs to the RUTBC family.
Subunit Structure
Interacts with RAB9A (GTP-bound form) and RAB9B (GTP-bound form); has much lower affinity for GDP-bound RAB9A and RAB9B. Interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A and RAP2B. No interaction with RAB27A.
Tissue Specificity
Mainly expressed in brain, heart and testis.
Function
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B.
Note
Recruited to cytoplasmic vesicle membranes via its interaction with Rab family members, such as RAB9A.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-SGSM1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
126 kDa
NCBI Official Full Name
small G protein signaling modulator 1 isoform 1
NCBI Official Synonym Full Names
small G protein signaling modulator 1
NCBI Official Symbol
SGSM1
NCBI Official Synonym Symbols
RUTBC2
NCBI Protein Information
small G protein signaling modulator 1; RUN and TBC1 domain containing 2; RUN and TBC1 domain-containing protein 2; small G protein signaling modulator 1 protein
UniProt Protein Name
Small G protein signaling modulator 1
Protein Family
UniProt Gene Name
SGSM1
UniProt Synonym Gene Names
KIAA1941; RUTBC2
UniProt Entry Name
SGSM1_HUMAN
Uniprot Description
SGSM1: Belongs to the RUTBC family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein regulator, misc.
Chromosomal Location of Human Ortholog: 22q11.23
Cellular Component: Golgi apparatus
Research Articles on SGSM1
Similar Products
Product Notes
The SGSM1 sgsm1 (Catalog #AAA9630713) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGSM1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SGSM1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the SGSM1 sgsm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGSM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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