Rabbit RMDN3 Polyclonal Antibody | anti-RMDN3 antibody
RMDN3 Antibody
Gene Names
RMDN3; RMD3; RMD-3; FAM82C; FAM82A2; ptpip51
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
RMDN3; Polyclonal Antibody; RMDN3 Antibody; Cerebral protein 10; FAM82C; formerly; Family with sequence similarity 82 member C; Family with sequence similarity 82; member A2; FLJ10579; hRMD 3; Microtubule associated protein; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase interacting protein 51; PTPIP51; Regulator of microtubule dynamics 3; Regulator of microtubule dynamics protein 3; RMD 3; RMD3; TCPTP interacting protein 51; anti-RMDN3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
RMDN3 Antibody detects endogenous levels of RMDN3.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RMDN3 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human RMDN3.
Conjugation
Unconjugated
Similarity
The transmembrane region is required for mitochondrial localization. Belongs to the RMDN family.
Subunit Structure
Interacts with PTPN2. Interacts with microtubules. Interacts with VAPB.
Tissue Specificity
Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed.
Function
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
Note
In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-RMDN3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,118 Da
NCBI Official Full Name
regulator of microtubule dynamics protein 3
NCBI Official Synonym Full Names
regulator of microtubule dynamics 3
NCBI Official Symbol
RMDN3
NCBI Official Synonym Symbols
RMD3; RMD-3; FAM82C; FAM82A2; ptpip51
NCBI Protein Information
regulator of microtubule dynamics protein 3; cerebral protein 10; TCPTP-interacting protein 51; microtubule-associated protein; family with sequence similarity 82, member C; family with sequence similarity 82, member A2; protein tyrosine phosphatase-inter
UniProt Protein Name
Regulator of microtubule dynamics protein 3
Protein Family
UniProt Gene Name
RMDN3
UniProt Synonym Gene Names
FAM82A2; FAM82C; PTPIP51; hucep-10; UNQ3122/PRO10274; RMD-3; hRMD-3
UniProt Entry Name
RMD3_HUMAN
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Product Notes
The RMDN3 rmdn3 (Catalog #AAA9630711) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RMDN3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RMDN3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the RMDN3 rmdn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RMDN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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