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Rabbit anti-Human, Mouse PAQR8 Polyclonal Antibody | anti-PAQR8 antibody

PAQR8 Antibody

Gene Names
PAQR8; MPRB; LMPB1; C6orf33
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PAQR8; Polyclonal Antibody; PAQR8 Antibody; C6orf33; LMPB1; Lysosomal membrane protein in brain 1; Membrane progestin receptor beta; mPR beta; MPRB; Progestin and adipoQ receptor family member 8; Progestin and adipoQ receptor family member VIII; anti-PAQR8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PAQR8 Antibody detects endogenous levels of PAQR8.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PAQR8 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PAQR8.
Conjugation
Unconjugated
Similarity
Belongs to the ADIPOR family.
Tissue Specificity
Highly expressed in the hypothalamus. Also expressed in spinal cord, kidney and testis.
Function
Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone.
Note
Colocalizes with a lysosomal protein CTSD/cathepsin D.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-PAQR8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,464 Da
NCBI Official Full Name
membrane progestin receptor beta
NCBI Official Synonym Full Names
progestin and adipoQ receptor family member 8
NCBI Official Symbol
PAQR8
NCBI Official Synonym Symbols
MPRB; LMPB1; C6orf33
NCBI Protein Information
membrane progestin receptor beta
UniProt Protein Name
Membrane progestin receptor beta
UniProt Gene Name
PAQR8
UniProt Synonym Gene Names
C6orf33; LMPB1; MPRB; mPR beta

Uniprot Description

PAQR8: Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation. Belongs to the ADIPOR family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p12.2

Cellular Component: plasma membrane

Molecular Function: steroid binding; steroid hormone receptor activity

Biological Process: response to steroid hormone stimulus

Research Articles on PAQR8

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Product Notes

The PAQR8 paqr8 (Catalog #AAA9629851) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAQR8 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PAQR8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PAQR8 paqr8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAQR8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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