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Rabbit anti-Human, Mouse ISG20 Polyclonal Antibody | anti-ISG20 antibody

ISG20 Antibody

Gene Names
ISG20; CD25; HEM45
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
ISG20; Polyclonal Antibody; ISG20 Antibody; CD25; Estrogen regulated transcript 45 protein; Estrogen-regulated transcript 45 protein; HEM45; Interferon stimulated exonuclease gene 20kDa; Interferon stimulated gene 20 kDa protein; Interferon-stimulated gene 20 kDa protein; Isg20; ISG20_HUMAN; Promyelocytic leukemia nuclear body associated protein; Promyelocytic leukemia nuclear body-associated protein ISG20; anti-ISG20 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
ISG20 Antibody detects endogenous levels of total ISG20.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-ISG20 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the exonuclease superfamily.
Subunit Structure
Associates with PML and SP100 in the PML NB complex. Associates with survival motor neuron protein (SMN)-containing macromolecular nuclear complexes and U1 and U2 snRNAs and U3 snoRNA.
Tissue Specificity
Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines.
Function
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-ISG20 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,199 Da
NCBI Official Full Name
interferon-stimulated gene 20 kDa protein isoform a
NCBI Official Synonym Full Names
interferon stimulated exonuclease gene 20kDa
NCBI Official Symbol
ISG20
NCBI Official Synonym Symbols
CD25; HEM45
NCBI Protein Information
interferon-stimulated gene 20 kDa protein; estrogen-regulated transcript 45 protein; promyelocytic leukemia nuclear body-associated protein ISG20
UniProt Protein Name
Interferon-stimulated gene 20 kDa protein
UniProt Gene Name
ISG20
UniProt Synonym Gene Names
HEM45
UniProt Entry Name
ISG20_HUMAN

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Product Notes

The ISG20 isg20 (Catalog #AAA9629634) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ISG20 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ISG20 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the ISG20 isg20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ISG20, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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