ODZ1 blocking peptide

ODZ1 Blocking Peptide

Cat. Num. AAA9621909

• Gene Names: TENM1; TNM; ODZ1; ODZ3; TNM1; TEN-M1
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: ODZ1; ODZ1 Blocking Peptide; Odz (odd Oz/ten m Drosophila) homolog 1; Odz (odd Oz/ten m Drosophila) homolog 3; ODZ 1; ODZ 3; Odz odd Oz/ten m homolog 1; ODZ3; OTTHUMP00000062724; Protein Odd Oz/ten m homolog 1; Ten 1; TEN M1; Ten1; Tenascin M; TenascinM; Teneurin 1; Teneurin1; TNM 1; TNM; TNM1; ODZ1 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for ODZ1 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ODZ1 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 253970444
• NCBI GeneID: 10178
• NCBI Accession #: NP_001156750
• NCBI GenBank Nucleotide #: NP_001156750.1
• UniProt Accession #: Q9UKZ4; Q5JZ17; B2RTR5
• Molecular Weight: Predicted: 301 kDa; ; Observed: 280 kDa
• NCBI Official Full Name: teneurin-1 isoform 1
• NCBI Official Synonym Full Names: teneurin transmembrane protein 1
• NCBI Official Symbol: TENM1
• NCBI Official Synonym Symbols: TNM; ODZ1; ODZ3; TNM1; TEN-M1
• NCBI Protein Information: teneurin-1; ten-1; teneurin 1; tenascin M1; tenascin-M1; odz, odd Oz/ten-m homolog 1; protein Odd Oz/ten-m homolog 1; odz, odd Oz/ten-m homolog 1(Drosophila); odz (odd Oz/ten-m, Drosophila) homolog 3
• UniProt Protein Name: Teneurin-1
• UniProt Gene Name: TENM1
• UniProt Synonym Gene Names: ODZ1; TNM1; Ten-1; Ten-m1; IDten-1; Ten-1 ICD; TCPA-1; Ten-1 ECD
• UniProt Entry Name: TEN1_HUMAN

NCBI Description

The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot Description

ODZ1: May function as a cellular signal transducer. Belongs to the tenascin family. Teneurin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: Golgi apparatus; cytoskeleton; nuclear matrix; integral to plasma membrane; perinuclear region of cytoplasm; endoplasmic reticulum; cytoplasm; extracellular region; plasma membrane; nuclear speck; nucleus

Molecular Function: heparin binding; protein homodimerization activity; protein heterodimerization activity

Biological Process: positive regulation of filopodium formation; nervous system development; negative regulation of cell proliferation; positive regulation of MAP kinase activity; transcription, DNA-dependent; positive regulation of actin filament polymerization; regulation of transcription from RNA polymerase III promoter; neuropeptide signaling pathway; immune response; positive regulation of peptidyl-serine phosphorylation