DDX21 blocking peptide
DDX21 Blocking Peptide
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NCBI and Uniprot Product Information
Uniprot Description
DDX21: a protein of the DEAD box helicase family. Unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
Protein type: EC 3.6.4.13; RNA processing; Helicase; Nucleolus; RNA-binding
Chromosomal Location of Human Ortholog: 10q21
Cellular Component: membrane; nucleolus; nucleus
Molecular Function: double-stranded RNA binding; ATP-dependent RNA helicase activity; ATP binding
Biological Process: osteoblast differentiation; response to exogenous dsRNA; metabolic process; response to virus