Septin 8 Blocking Peptide | SEPT8 blocking peptide

Septin 8 Blocking Peptide

Cat. Num. AAA9619694

• Gene Names: SEPT8; SEP2
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: Septin 8; Septin 8 Blocking Peptide; KIAA0202; OTTHUMP00000211755; SEP 2; SEP2; SEPT 8; SEPT8; Septin8; SEPT8 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for SEPT8 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SEPT8 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 149363689
• NCBI GeneID: 23176
• NCBI Accession #: NP_001092281.1
• NCBI GenBank Nucleotide #: NM_001098811.1
• UniProt Accession #: Q92599; Q8IX36; Q8IX37; Q9BVB3; A6NC65; A6NKP6; F6W7K9
• Molecular Weight: 51,178 Da
• NCBI Official Full Name: septin-8 isoform a
• NCBI Official Synonym Full Names: septin 8
• NCBI Official Symbol: SEPT8
• NCBI Official Synonym Symbols: SEP2
• NCBI Protein Information: septin-8
• UniProt Protein Name: Septin-8
• UniProt Gene Name: SEPT8
• UniProt Synonym Gene Names: KIAA0202
• UniProt Entry Name: SEPT8_HUMAN

NCBI Description

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

SEPT8: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. Belongs to the septin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Hydrolase

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: cytoskeleton; cytoplasm

Molecular Function: protein binding; GTP binding

Biological Process: cell cycle