Western Blot (WB)
(Western blot analysis of extracts from Jurkat cells, using MGAT5B Antibody. The lane on the left was treated with blocking peptide.)
Rabbit MGAT5B Polyclonal Antibody | anti-MGAT5B antibody
MGAT5B Antibody
Predicted: Pig, Bovine, Sheep, Dog
Predicted: Pig, Bovine, Sheep, Dog
Western Blot (WB)
(Western blot analysis of extracts from Jurkat cells, using MGAT5B Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Jurkat cells, using MGAT5B Antibody. The lane on the left was treated with blocking peptide.)
Similarity: Belongs to the glycosyltransferase 18 family.
NCBI and Uniprot Product Information
Predicted: 90 kDa
NCBI Description
The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
Uniprot Description
MGAT5B: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N- acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. Belongs to the glycosyltransferase 18 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transferase; EC 2.4.1.155; Glycan Metabolism - N-glycan biosynthesis
Chromosomal Location of Human Ortholog: 17q25.2
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: protein binding; alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity; metal ion binding
Biological Process: protein amino acid N-linked glycosylation
Research Articles on MGAT5B
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Product Notes
The MGAT5B mgat5b (Catalog #AAA9611898) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MGAT5B Antibody reacts with Human, Rat Predicted: Pig, Bovine, Sheep, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's MGAT5B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MGAT5B mgat5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MGAT5B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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