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Western Blot (WB) (Western blot analysis of extracts from mouse muscle, using ACSL1 Antibody. Lane 1 was treated with the blocking peptide.)

Rabbit ACSL1 Polyclonal Antibody | anti-ACSL1 antibody

ACSL1 Antibody

Gene Names
ACSL1; ACS1; LACS; FACL1; FACL2; LACS1; LACS2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ACSL1; Polyclonal Antibody; ACSL1 Antibody; ACS 1; ACS1; ACSL 1; ACSL1_HUMAN; Acyl CoA synthetase 1; Acyl CoA synthetase long chain family member 1; Acyl-CoA synthetase 1; FACL 1; FACL 2; FACL1; FACL2; Fatty acid Coenzyme A ligase long chain 1; Fatty acid Coenzyme A ligase long chain 2; LACS 1; LACS 2; LACS; LACS1; LACS2; Lignoceroyl CoA synthase; Long chain acyl CoA synthetase 1; Long chain acyl CoA synthetase 2; Long chain fatty acid CoA ligase 1; Long chain fatty acid CoA ligase 2; Long chain fatty acid coenzyme A ligase 1; Long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; Long-chain fatty acid-CoA ligase 2; Long-chain-fatty-acid--CoA ligase 1; Palmitoyl CoA ligase 1; Palmitoyl CoA ligase 2; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; Paltimoyl CoA ligase 1; anti-ACSL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ACSL1 antibody detects endogenous levels of total ACSL1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
698
Applicable Applications for anti-ACSL1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human ACSL1
Subcellular Location
Mitochondrion Outer Membrane. Peroxisome Membrane. Microsome Membrane. Endoplasmic Reticulum Membrane.
Tissue Specificity
Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.
Predicted Cross Reactivity
Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Similarity
Bovine (91%), Horse (100%), Sheep (100%), Dog (92%), Chicken (100%), Xenopus (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from mouse muscle, using ACSL1 Antibody. Lane 1 was treated with the blocking peptide.)

Western Blot (WB) (Western blot analysis of extracts from mouse muscle, using ACSL1 Antibody. Lane 1 was treated with the blocking peptide.)

Western Blot (WB)

(Western blot analysis of ACSL1 using MCF7 whole cell lysates)

Western Blot (WB) (Western blot analysis of ACSL1 using MCF7 whole cell lysates)
Related Product Information for anti-ACSL1 antibody
Function: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 78 kDa
Predicted: 78 kDa
NCBI Official Full Name
long-chain-fatty-acid--CoA ligase 1 isoform a
NCBI Official Synonym Full Names
acyl-CoA synthetase long chain family member 1
NCBI Official Symbol
ACSL1
NCBI Official Synonym Symbols
ACS1; LACS; FACL1; FACL2; LACS1; LACS2
NCBI Protein Information
long-chain-fatty-acid--CoA ligase 1
UniProt Protein Name
Long-chain-fatty-acid--CoA ligase 1
UniProt Gene Name
ACSL1
UniProt Synonym Gene Names
FACL1; FACL2; LACS; LACS1; LACS2; ACS1; LACS 1; LACS 2

NCBI Description

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Uniprot Description

Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.

Research Articles on ACSL1

Similar Products

Product Notes

The ACSL1 acsl1 (Catalog #AAA9609922) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACSL1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ACSL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the ACSL1 acsl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACSL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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