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Western Blot (WB) (Western blot analysis of RALGAPA1 using HuvEc whole cell lysates)

Rabbit RALGAPA1 Polyclonal Antibody | anti-RALGAPA1 antibody

RALGAPA1 Antibody

Gene Names
RALGAPA1; p240; GRIPE; GARNL1; TULIP1; RalGAPalpha1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
RALGAPA1; Polyclonal Antibody; RALGAPA1 Antibody; DKFZp566D133; DKFZp667F074; GAP related interacting partner to E12; GAP related interacting protein to E12; GARN L1; GARNL 1; GRIPE; GTPase activating RANGAP domain like 1; GTPase activating Rap/RanGAP domain like 1; KIAA0884; p240; Ral GTPase activating protein catalytic alpha subunit 1; Ral GTPase activating protein subunit alpha 1; Ral GTPase activating protein; alpha subunit 1 (catalytic); RalGAPalpha1; Tuberin like protein 1; TULIP 1; TULIP1; anti-RALGAPA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
RALGAPA1 antibody detects endogenous levels of total RALGAPA1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
2049
Applicable Applications for anti-RALGAPA1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human RALGAPA1
Subcellular Location
Nucleus
Tissue Specificity
Widely expressed.
Predicted Cross Reactivity
Bovine, Horse, Sheep, Rabbit
Similarity
Bovine (82%), Horse (100%), Sheep (82%), Rabbit (82%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of RALGAPA1 using HuvEc whole cell lysates)

Western Blot (WB) (Western blot analysis of RALGAPA1 using HuvEc whole cell lysates)
Related Product Information for anti-RALGAPA1 antibody
Function: Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.
Subunit Structure: Component of the heterodimeric RalGAP1 complex with RALGAPB. Heterodimerization is required for activity. Interacts with the HLH region of TCF3/isoform E12 (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 230 kDa
Predicted: 230 kDa
NCBI Official Full Name
ral GTPase-activating protein subunit alpha-1 isoform 3
NCBI Official Synonym Full Names
Ral GTPase activating protein catalytic alpha subunit 1
NCBI Official Symbol
RALGAPA1
NCBI Official Synonym Symbols
p240; GRIPE; GARNL1; TULIP1; RalGAPalpha1
NCBI Protein Information
ral GTPase-activating protein subunit alpha-1
UniProt Protein Name
Ral GTPase-activating protein subunit alpha-1
UniProt Gene Name
RALGAPA1
UniProt Synonym Gene Names
GARNL1; KIAA0884; TULIP1; GRIPE

NCBI Description

This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]

Uniprot Description

Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.

Research Articles on RALGAPA1

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Product Notes

The RALGAPA1 ralgapa1 (Catalog #AAA9609865) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RALGAPA1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RALGAPA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the RALGAPA1 ralgapa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RALGAPA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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