Western Blot (WB)
(Western blot analysis of BAGE5 using HeLa whole cell lysates)
Rabbit BAGE5 Polyclonal Antibody | anti-BAGE5 antibody
BAGE5 Antibody
Gene Names
BAG5; BAG-5
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
BAGE5; Polyclonal Antibody; BAGE5 Antibody; BAG family molecular chaperone regulator 5; BAG-5; BAG5; BAG5_HUMAN; Bcl 2 associated athanogene 5; Bcl-2-associated athanogene 5; BCL2 associated athanogene 5; KIAA0873; anti-BAGE5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
BAGE5 antibody detects endogenous levels of total BAGE5
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
447
Applicable Applications for anti-BAGE5 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human BAGE5
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Dog
Similarity
Pig (91%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of BAGE5 using HeLa whole cell lysates)
Western Blot (WB)
(Western blot analysis of BAGE5 using HeLa whole cell lysates)
Related Product Information for anti-BAGE5 antibody
Function: Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
Subunit Structure: Binds to the ATPase domain of HSP/HSC70 chaperones. Binds PRKN.
Similarity: The fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
Subunit Structure: Binds to the ATPase domain of HSP/HSC70 chaperones. Binds PRKN.
Similarity: The fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 51 kDa
Predicted: 52 kDa
Predicted: 52 kDa
NCBI Official Full Name
BAG family molecular chaperone regulator 5 isoform b
NCBI Official Synonym Full Names
BCL2 associated athanogene 5
NCBI Official Symbol
BAG5
NCBI Official Synonym Symbols
BAG-5
NCBI Protein Information
BAG family molecular chaperone regulator 5
UniProt Protein Name
BAG family molecular chaperone regulator 5
Protein Family
UniProt Gene Name
BAG5
UniProt Synonym Gene Names
KIAA0873; BAG-5
NCBI Description
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN (). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
Research Articles on BAGE5
Similar Products
Product Notes
The BAGE5 bag5 (Catalog #AAA9609582) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BAGE5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BAGE5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the BAGE5 bag5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAGE5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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