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Western Blot (WB) (Western blot analysis of Bone Sialoprotein using K562 whole lysates.)

Rabbit Bone Sialoprotein Polyclonal Antibody | anti-BSP antibody

Bone Sialoprotein Antibody

Gene Names
IBSP; BSP; BNSP; SP-II; BSP-II
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Peptide affinity purification
Synonyms
Bone Sialoprotein; Polyclonal Antibody; Bone Sialoprotein Antibody; BNSP; Bone sialoprotein 2; Bone sialoprotein II; BSP II; BSPII; Cell binding sialoprotein; Cell-binding sialoprotein; IBSP; Integrin binding sialoprotein; Integrin-binding sialoprotein; SIAL_HUMAN; SPII; anti-BSP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Bone Sialoprotein antibody detects endogenous levels of total Bone Sialoprotein
Purity/Purification
Peptide affinity purification
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
317
Applicable Applications for anti-BSP antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human Bone Sialoprotein, corresponding to a region within the internal amino acids.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of Bone Sialoprotein using K562 whole lysates.)

Western Blot (WB) (Western blot analysis of Bone Sialoprotein using K562 whole lysates.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 35 kDa
Predicted: 36 kDa
NCBI Official Full Name
bone sialoprotein 2
NCBI Official Synonym Full Names
integrin binding sialoprotein
NCBI Official Symbol
IBSP
NCBI Official Synonym Symbols
BSP; BNSP; SP-II; BSP-II
NCBI Protein Information
bone sialoprotein 2
UniProt Protein Name
Bone sialoprotein 2
Protein Family
UniProt Gene Name
IBSP
UniProt Synonym Gene Names
BNSP; BSP II

NCBI Description

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]

Uniprot Description

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.

Research Articles on BSP

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Product Notes

The BSP ibsp (Catalog #AAA9608317) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bone Sialoprotein Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Bone Sialoprotein can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the BSP ibsp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bone Sialoprotein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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