Western Blot (WB)
(Western blot analysis of Cytochrome P450 51A1 using A431 whole cell lysates)
Rabbit anti-Human Cytochrome P450 51A1 Polyclonal Antibody | anti-CYP51A1 antibody
Cytochrome P450 51A1 Antibody
Gene Names
CYP51A1; LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
Cytochrome P450 51A1; Polyclonal Antibody; Cytochrome P450 51A1 Antibody; CP51; CP51A_HUMAN; CYP51; CYP51A1; CYPL1; CYPLI; Cytochrome P450 51; Cytochrome P450 family 51 subfamily A member 1; Cytochrome P450 family 51 subfamily A polypeptide 1; Cytochrome P450; 51 (lanosterol 14 alpha demethylase); Cytochrome P450-14DM; Cytochrome P45014DM; Cytochrome P450LI; Lanosterol 14-alpha demethylase; LDM; P450 14DM; P450L1; Sterol 14-alpha demethylase; anti-CYP51A1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Cytochrome P450 51A1 antibody detects endogenous levels of total Cytochrome P450 51A1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
509
Applicable Applications for anti-CYP51A1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
Immunogen
A synthesized peptide
Subcellular Location
Endoplasmic Reticulum Membrane. Microsome Membrane.
Tissue Specificity
Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of Cytochrome P450 51A1 using A431 whole cell lysates)
Western Blot (WB)
(Western blot analysis of Cytochrome P450 51A1 using A431 whole cell lysates)
Related Product Information for anti-CYP51A1 antibody
Function: Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4, 4'-dimethyl cholesta-8, 14, 24-triene-3-beta-ol.
Similarity: Belongs to the cytochrome P450 family.
Similarity: Belongs to the cytochrome P450 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 57 kD
Predicted: 57 kDa
Predicted: 57 kDa
NCBI Official Full Name
lanosterol 14-alpha demethylase isoform 1
NCBI Official Synonym Full Names
cytochrome P450 family 51 subfamily A member 1
NCBI Official Symbol
CYP51A1
NCBI Official Synonym Symbols
LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM
NCBI Protein Information
lanosterol 14-alpha demethylase
UniProt Protein Name
Lanosterol 14-alpha demethylase
UniProt Gene Name
CYP51A1
UniProt Synonym Gene Names
CYP51; LDM; Cytochrome P45014DM
NCBI Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Uniprot Description
Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
Research Articles on CYP51A1
Similar Products
Product Notes
The CYP51A1 cyp51a1 (Catalog #AAA9605047) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 51A1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome P450 51A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000. Researchers should empirically determine the suitability of the CYP51A1 cyp51a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome P450 51A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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