Western Blot (WB)
(Western blot analysis of PMS1 expression in A549 cell line lysate, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse PMS1 Polyclonal Antibody | anti-PMS1 antibody
PMS1 Antibody
Gene Names
PMS1; MLH2; PMSL1; hPMS1; HNPCC3
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PMS1; Polyclonal Antibody; PMS1 Antibody; DNA mismatch repair protein PMS1; FLJ98259; HNPCC3; hPMS1; Human homolog of yeast mutL; Mismatch repair gene PMSL1; pms1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMS1 postmeiotic segregation increased 1; PMS1 protein homolog 1; PMS1_HUMAN; PMSL1; Rhabdomyosarcoma antigen MU RMS 40.10B; Rhabdomyosarcoma antigen MU RMS 40.10E; anti-PMS1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
PMS1 antibody detects endogenous levels of total PMS1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
932
Applicable Applications for anti-PMS1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
A synthesized peptide
Subcellular Location
Nucleus.
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of PMS1 expression in A549 cell line lysate, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of PMS1 expression in A549 cell line lysate, The lane on the left is treated with the antigen-specific peptide.)
Immunohistochemistry (IHC)
(MBS9603905 at 1/100 staining Mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Immunohistochemistry (IHC)
(MBS9603905 at 1/100 staining Mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Related Product Information for anti-PMS1 antibody
Description: Probably involved in the repair of mismatches in DNA.
Subunit Structure: The MutL-beta complex is a heterodimer of PMS1 and MLH1.
Similarity: Belongs to the DNA mismatch repair MutL/HexB family.
Subunit Structure: The MutL-beta complex is a heterodimer of PMS1 and MLH1.
Similarity: Belongs to the DNA mismatch repair MutL/HexB family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 105 kDa
Predicted: 106 kDa
Predicted: 106 kDa
NCBI Official Full Name
PMS1 protein homolog 1 isoform a
NCBI Official Synonym Full Names
PMS1 homolog 1, mismatch repair system component
NCBI Official Symbol
PMS1
NCBI Official Synonym Symbols
MLH2; PMSL1; hPMS1; HNPCC3
NCBI Protein Information
PMS1 protein homolog 1
UniProt Protein Name
PMS1 protein homolog 1
Protein Family
UniProt Gene Name
PMS1
UniProt Synonym Gene Names
PMSL1
NCBI Description
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Uniprot Description
Probably involved in the repair of mismatches in DNA.
Research Articles on PMS1
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Product Notes
The PMS1 pms1 (Catalog #AAA9603905) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PMS1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PMS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PMS1 pms1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PMS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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