ATP-citrate synthase (Acly) Recombinant Protein | Acly recombinant protein

Recombinant Rat ATP-citrate synthase (Acly) , partial

• Gene Names: Acly; ACL; Clatp
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: ATP-citrate synthase (Acly); Recombinant Rat ATP-citrate synthase (Acly); partial; Acly recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,091

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Acly recombinant protein

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 161760632
• NCBI GeneID: 24159
• NCBI Accession #: NP_001104565.1
• NCBI GenBank Nucleotide #: NM_001111095.1
• UniProt Accession #: P16638; Q497C7; Q8VIQ1
• Molecular Weight: 119,704 Da
• NCBI Official Full Name: ATP-citrate synthase isoform 2
• NCBI Official Synonym Full Names: ATP citrate lyase
• NCBI Official Symbol: Acly
• NCBI Official Synonym Symbols: ACL; Clatp
• NCBI Protein Information: ATP-citrate synthase
• UniProt Protein Name: ATP-citrate synthase
• Protein Family: ATP-citrate synthase
• UniProt Gene Name: Acly

NCBI Description

catalyzes the synthesis of cytosolic acetyl-CoA; plays a role in lipid and cholesterol metabolism [RGD, Feb 2006]

Uniprot Description

ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.