Interferon-induced GTP-binding protein Mx1 (Mx1) Recombinant Protein | Mx1 recombinant protein
Recombinant Mouse Interferon-induced GTP-binding protein Mx1 (Mx1)
Gene Names
Mx1; Mx; Mx-1; AI893580
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Interferon-induced GTP-binding protein Mx1 (Mx1); Recombinant Mouse Interferon-induced GTP-binding protein Mx1 (Mx1); Mx1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-631, Full length protein
Sequence
MDSVNNLCRHYEEKVRPCIDLIDTLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLKEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGVLTKPDLVDRGAEGKVLDVMRNLVYPLKKGYMIVKCRGQQDIQEQLSLTEAFQKEQVFFKDHSYFSILLEDGKATVPCLAERLTEELTSHICKSLPLLEDQINSSHQSASEELQKYGADIPEDDRTRMSFLVNKISAFNRNIMNLIQAQETVSEGDSRLFTKLRNEFLAWDDHIEEYFKKDSPEVQSKMKEFENQYRGRELPGFVDYKAFESIIKKRVKALEESAVNMLRRVTKMVQTAFVKILSNDFGDFLNLCCTAKSKIKEIRLNQEKEAENLIRLHFQMEQIVYCQDQVYKETLKTIREKEAEKEKTKALINPATFQNNSQFPQKGLTTTEMTQHLKAYYQECRRNIGRQIPLIIQYFILKTFGEEIEKMMLQLLQDTSKCSWFLEEQSDTREKKKFLKRRLLRLDEARQKLAKFSD
Sequence Length
631
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
72,038 Da
NCBI Official Full Name
interferon-induced GTP-binding protein Mx1
NCBI Official Synonym Full Names
MX dynamin-like GTPase 1
NCBI Official Symbol
Mx1
NCBI Official Synonym Symbols
Mx; Mx-1; AI893580
NCBI Protein Information
interferon-induced GTP-binding protein Mx1
UniProt Protein Name
Interferon-induced GTP-binding protein Mx1
Protein Family
UniProt Gene Name
Mx1
NCBI Description
This gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to the influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a deletion or a nonsense mutation that results in a non-functional gene product. [provided by RefSeq, Aug 2015]
Uniprot Description
Interferon-induced dynamin-like GTPase with antiviral activity against influenza A virus, (IAV), influenza B virus (IBV) and Thogoto virus (THOV). Inhibits FLUAV by interfering with the process of primary transcription, probably by affecting the viral polymerase function.
Research Articles on Mx1
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Product Notes
The Mx1 mx1 (Catalog #AAA957568) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-631, Full length protein. The amino acid sequence is listed below: MDSVNNLCRH YEEKVRPCID LIDTLRALGV EQDLALPAIA VIGDQSSGKS SVLEALSGVA LPRGSGIVTR CPLVLKLRKL KEGEEWRGKV SYDDIEVELS DPSEVEEAIN KGQNFIAGVG LGISDKLISL DVSSPNVPDL TLIDLPGITR VAVGNQPADI GRQIKRLIKT YIQKQETINL VVVPSNVDIA TTEALSMAQE VDPEGDRTIG VLTKPDLVDR GAEGKVLDVM RNLVYPLKKG YMIVKCRGQQ DIQEQLSLTE AFQKEQVFFK DHSYFSILLE DGKATVPCLA ERLTEELTSH ICKSLPLLED QINSSHQSAS EELQKYGADI PEDDRTRMSF LVNKISAFNR NIMNLIQAQE TVSEGDSRLF TKLRNEFLAW DDHIEEYFKK DSPEVQSKMK EFENQYRGRE LPGFVDYKAF ESIIKKRVKA LEESAVNMLR RVTKMVQTAF VKILSNDFGD FLNLCCTAKS KIKEIRLNQE KEAENLIRLH FQMEQIVYCQ DQVYKETLKT IREKEAEKEK TKALINPATF QNNSQFPQKG LTTTEMTQHL KAYYQECRRN IGRQIPLIIQ YFILKTFGEE IEKMMLQLLQ DTSKCSWFLE EQSDTREKKK FLKRRLLRLD EARQKLAKFS D. It is sometimes possible for the material contained within the vial of "Interferon-induced GTP-binding protein Mx1 (Mx1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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