Lysosome-associated membrane glycoprotein 2 (Lamp2) Recombinant Protein | Lamp2 recombinant protein

Recombinant Rat Lysosome-associated membrane glycoprotein 2 (Lamp2)

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Lysosome-associated membrane glycoprotein 2 (Lamp2); Recombinant Rat Lysosome-associated membrane glycoprotein 2 (Lamp2); Recombinant Lysosome-associated membrane glycoprotein 2 (Lamp2); Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B LGP-110 LGP-96 Lysosomal membrane glycoprotein type B; LGP-B C; Lamp2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 26-376

• Species: Rattus norvegicus (Rat)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 126382
• NCBI GeneID: 24944
• UniProt Accession #: P17046
• Molecular Weight: 45,164 Da
• NCBI Official Full Name: Lysosome-associated membrane glycoprotein 2
• NCBI Official Synonym Full Names: lysosomal-associated membrane protein 2
• NCBI Official Symbol: Lamp2
• NCBI Protein Information: lysosome-associated membrane glycoprotein 2; LGP-B; LAMP-2; LGP-96; LGP-110; lysosomal membrane glycoprotein 2; CD107 antigen-like family member B; lysosomal membrane glycoprotein type B; lysosome-associated membrane protein 2
• UniProt Protein Name: Lysosome-associated membrane glycoprotein 2
• Protein Family: Lysosome-associated membrane glycoprotein
• UniProt Gene Name: Lamp2
• UniProt Synonym Gene Names: Lamp-2; LAMP-2; Lysosome-associated membrane protein 2; LGP-B
• UniProt Entry Name: LAMP2_RAT

NCBI Description

intrinsic lysosomal membrane protein [RGD, Feb 2006]

Uniprot Description

Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: This protein shuttles between lysosomes, endosomes, and the plasma membrane.

Post-translational modification: O- and N-glycosylated; some of the N-glycans attached to Lamp-2 are polylactosaminoglycans

By similarity.

Sequence similarities: Belongs to the LAMP family.