Keratin, type I cytoskeletal 18 (Krt18) Recombinant Protein | Krt18 recombinant protein
Recombinant Mouse Keratin, type I cytoskeletal 18 (Krt18)
Gene Names
Krt18; K18; CK18; Krt1-18
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Keratin; type I cytoskeletal 18 (Krt18); Recombinant Mouse Keratin; Krt18 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-423, Full length protein
Sequence
SFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSVWGGSVGSAGLAGMGGIQTEKETMQDLNDRLASYLDKVKSLETENRRLESKIREHLEKKGPQGVRDWGHYFKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEALAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLTELRRTLQTLEIDLDSMKNQNINLENSLGDVEARYKAQMEQLNGVLLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLNDALDSSNSMQTVQKTTTRKIVDGRVVSETNDTRVLRH
Sequence Length
422
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Krt18 recombinant protein
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,538 Da
NCBI Official Full Name
keratin, type I cytoskeletal 18
NCBI Official Synonym Full Names
keratin 18
NCBI Official Symbol
Krt18
NCBI Official Synonym Symbols
K18; CK18; Krt1-18
NCBI Protein Information
keratin, type I cytoskeletal 18
UniProt Protein Name
Keratin, type I cytoskeletal 18
Protein Family
UniProt Gene Name
Krt18
UniProt Synonym Gene Names
Kerd; Krt1-18; Keratin D; CK-18; K18
Uniprot Description
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Research Articles on Krt18
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Product Notes
The Krt18 krt18 (Catalog #AAA952921) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-423, Full length protein. The amino acid sequence is listed below: SFTTRSTTFS TNYRSLGSVR TPSQRVRPAS SAASVYAGAG GSGSRISVSR SVWGGSVGSA GLAGMGGIQT EKETMQDLND RLASYLDKVK SLETENRRLE SKIREHLEKK GPQGVRDWGH YFKIIEDLRA QIFANSVDNA RIVLQIDNAR LAADDFRVKY ETELAMRQSV ESDIHGLRKV VDDTNITRLQ LETEIEALKE ELLFMKKNHE EEVQGLEAQI ASSGLTVEVD APKSQDLSKI MADIRAQYEA LAQKNREELD KYWSQQIEES TTVVTTKSAE IRDAETTLTE LRRTLQTLEI DLDSMKNQNI NLENSLGDVE ARYKAQMEQL NGVLLHLESE LAQTRAEGQR QAQEYEALLN IKVKLEAEIA TYRRLLEDGE DFSLNDALDS SNSMQTVQKT TTRKIVDGRV VSETNDTRVL RH. It is sometimes possible for the material contained within the vial of "Keratin, type I cytoskeletal 18 (Krt18), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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