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Western Blot (WB) (Western blot analysis of lysate from 4T1 cells, using SERPINA3 Antibody.)

Rabbit anti-Human SERPINA3 Polyclonal Antibody | anti-SERPINA3 antibody

SERPINA3 Antibody

Gene Names
SERPINA3; ACT; AACT; GIG24; GIG25
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Synonyms
SERPINA3; Polyclonal Antibody; SERPINA3 Antibody; anti-SERPINA3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
SERPINA3 Antibody detects endogenous levels of SERPINA3 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
95
Applicable Applications for anti-SERPINA3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA3.
Immunogen Range
251-300
Preparation and Storage
Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysate from 4T1 cells, using SERPINA3 Antibody.)

Western Blot (WB) (Western blot analysis of lysate from 4T1 cells, using SERPINA3 Antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
12
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47 kDa
NCBI Official Full Name
alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin family A member 3
NCBI Official Symbol
SERPINA3
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25
NCBI Protein Information
alpha-1-antichymotrypsin
UniProt Protein Name
Alpha-1-antichymotrypsin
Protein Family
UniProt Gene Name
SERPINA3
UniProt Synonym Gene Names
AACT; ACT

NCBI Description

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]

Uniprot Description

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

Research Articles on SERPINA3

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Product Notes

The SERPINA3 serpina3 (Catalog #AAA9507491) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SERPINA3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SERPINA3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the SERPINA3 serpina3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPINA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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