Human Progesterone Receptor ELISA Kit | PGR elisa kit
Progesterone Receptor TFact DNA-Binding ELISA Kit
Testing Data
(The TFact Progesterone Receptor DNA-Binding ELISA detects active Progesterone Receptor in Hela, Jurkat and MCF7 Nuclear Extract. The Hela, MCF7 and Jurkat cells were grown 3 days respectively in DMEM and RPMI 1640 with 10% FBS and harvested for nuclear extract. The Hela cells with UV stimulation were irradiated by UV (100J/M2) before harvest.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
Uniprot Description
PR: a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of Human Ortholog: 11q22.1
Cellular Component: cytosol; mitochondrial outer membrane; nucleoplasm
Molecular Function: ATPase binding; DNA binding; enzyme binding; identical protein binding; ligand-dependent nuclear receptor activity; protein binding; steroid binding; steroid hormone receptor activity; zinc ion binding
Biological Process: alveolus development; cell-cell signaling; epithelial cell maturation; negative regulation of gene expression; ovulation from ovarian follicle; paracrine signaling; positive regulation of transcription from RNA polymerase II promoter; progesterone receptor signaling pathway; regulation of epithelial cell proliferation; signal transduction; transcription initiation from RNA polymerase II promoter
Disease: Progesterone Resistance
Research Articles on PGR
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Product Notes
The Human PGR pgr (Catalog #AAA9502238) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502238 ELISA Kit recognizes Human PGR. It is sometimes possible for the material contained within the vial of "Progesterone Receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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