CDC37 elisa kit
Phospho-CDC37 (Ser13) Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
Uniprot Description
CDC37: a molecular chaperone that functions in cell signal transduction. Forms complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. Also interacts with androgen receptor. It is thought to play a critical role in directing Hsp90 to its target kinases.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cytoplasm; cytosol; extracellular exosome; HSP90-CDC37 chaperone complex
Molecular Function: chaperone binding; heat shock protein binding; Hsp90 protein binding; kinase binding; protein binding; protein kinase binding; protein kinase regulator activity; protein tyrosine kinase activity; unfolded protein binding
Biological Process: ERBB2 signaling pathway; peptidyl-tyrosine phosphorylation; positive regulation of mitophagy in response to mitochondrial depolarization; posttranscriptional regulation of gene expression; protein folding; protein stabilization; protein targeting; regulation of cyclin-dependent protein kinase activity
Research Articles on CDC37
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Product Notes
The Human, Mouse, Rat CDC37 cdc37 (Catalog #AAA9501337) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501337 ELISA Kit recognizes Human, Mouse, Rat CDC37. It is sometimes possible for the material contained within the vial of "CDC37, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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