Human, Mouse MSK2 ELISA Kit | MSK2 elisa kit
MSK2 Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Uniprot Description
MSK2: an AGC kinase of the RSK family. Has two kinase domains connected by a regulatory linker region. Phosphorylates H3 and HMG-14 in response to growth factors and cellular stress.
Protein type: AGC group; EC 2.7.11.1; Kinase, protein; MSK subfamily; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); RSK family
Chromosomal Location of Human Ortholog: 11q13.1
Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus
Molecular Function: ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activity; ribosomal protein S6 kinase activity
Biological Process: histone phosphorylation; inflammatory response; negative regulation of cytokine production; positive regulation of CREB transcription factor activity; positive regulation of histone acetylation; positive regulation of histone phosphorylation; positive regulation of NF-kappaB transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; regulation of transcription, DNA-templated
Research Articles on MSK2
Similar Products
Product Notes
The Human, Mouse MSK2 rps6ka4 (Catalog #AAA9500408) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9500408 ELISA Kit recognizes Human, Mouse MSK2. It is sometimes possible for the material contained within the vial of "MSK2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
