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Rabbit anti-Human Actin-Related Protein 2/3 Complex Subunit 3 Polyclonal Antibody | anti-ARPC3 antibody

Actin-Related Protein 2/3 Complex Subunit 3 Polyclonal Conjugated Antibody

Gene Names
ARPC3; ARC21; p21-Arc
Reactivity
Human
Applications
Most Applications
Synonyms
Actin-Related Protein 2/3 Complex Subunit 3; Polyclonal Antibody; Actin-Related Protein 2/3 Complex Subunit 3 Polyclonal Conjugated Antibody; anti-ARPC3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Actin-related protein 2/3 complex subunit 3 polyclonal antibody.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-ARPC3 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Recombinant human Actin-related protein 2/3 complex subunit 3 protein
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-ARPC3 antibody
p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
178
NCBI Official Full Name
Actin-related protein 2/3 complex subunit 3
NCBI Official Synonym Full Names
actin related protein 2/3 complex, subunit 3, 21kDa
NCBI Official Symbol
ARPC3
NCBI Official Synonym Symbols
ARC21; p21-Arc
NCBI Protein Information
actin-related protein 2/3 complex subunit 3; arp2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21
UniProt Protein Name
Actin-related protein 2/3 complex subunit 3
UniProt Gene Name
ARPC3
UniProt Synonym Gene Names
ARC21; p21-ARC
UniProt Entry Name
ARPC3_HUMAN

NCBI Description

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Uniprot Description

ARPC3: one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12q24.11

Cellular Component: Arp2/3 protein complex; focal adhesion; membrane; lamellipodium; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility

Research Articles on ARPC3

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Product Notes

The ARPC3 arpc3 (Catalog #AAA9450801) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Actin-Related Protein 2/3 Complex Subunit 3 Polyclonal Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Actin-Related Protein 2/3 Complex Subunit 3 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the ARPC3 arpc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Actin-Related Protein 2/3 Complex Subunit 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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