Rabbit anti-Human UPP1 Polyclonal Antibody | anti-UPP1 antibody

UPP1 Polyclonal Antibody

Cat. Num. AAA9431748

• Gene Names: UPP1; UP; UPP; UPASE; UDRPASE
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity purification
• Synonyms: UPP1; Polyclonal Antibody; UPP1 Polyclonal Antibody; UDRPASE; UP; UPASE; UPP; uridine phosphorylase 1; anti-UPP1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 50% glycerol, pH7.4

• Applicable Applications for anti-UPP1 antibody: Western Blot (WB)
• Application Notes: WB: 1:1000-1:2000
• Immunogen: Recombinant fusion protein of human UPP1 (NP_001274357.1).
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using UPP1 Antibody.)

Related Product Information for anti-UPP1 antibody

This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides.

Product Categories/Family for anti-UPP1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 566006090
• NCBI GeneID: 7378
• NCBI Accession #: NP_001274357.1
• NCBI GenBank Nucleotide #: NM_001287428.1
• UniProt Accession #: Q16831
• Molecular Weight: Molecular Mass: 21.3 kDa; Actual Protein Molecular Mass: 18; 41 kDa
• NCBI Official Full Name: uridine phosphorylase 1 isoform b
• NCBI Official Synonym Full Names: uridine phosphorylase 1
• NCBI Official Symbol: UPP1
• NCBI Official Synonym Symbols: UP; UPP; UPASE; UDRPASE
• NCBI Protein Information: uridine phosphorylase 1
• UniProt Protein Name: Uridine phosphorylase 1
• Protein Family: Uridine phosphorylase
• UniProt Gene Name: UPP1
• UniProt Synonym Gene Names: UP; UPase 1; UrdPase 1
• UniProt Entry Name: UPP1_HUMAN

NCBI Description

This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]

Uniprot Description

UPP1: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.2.3; Xenobiotic Metabolism - drug metabolism - other enzymes; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: cytosol

Molecular Function: uridine phosphorylase activity

Biological Process: cellular response to glucose starvation; pyrimidine nucleoside catabolic process; uridine metabolic process; pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide catabolic process; pyrimidine nucleoside salvage