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Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47688(KCNN2 Antibody) at dilution 1/65.(Original magnification: 200))

Rabbit KCNN2 Polyclonal Antibody | anti-KCNN2 antibody

KCNN2 Antibody

Gene Names
KCNN2; SK2; hSK2; SKCA2; KCa2.2; SKCa 2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
KCNN2; Polyclonal Antibody; KCNN2 Antibody; SK2; hSK2; SKCA2; KCa2.2; SKCa 2; anti-KCNN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total KCNN2 protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.9 mg/mL (varies by lot)
Sequence Length
231
Applicable Applications for anti-KCNN2 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-300
Immunogen
Synthetic peptide of human KCNN2
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47688(KCNN2 Antibody) at dilution 1/65.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47688(KCNN2 Antibody) at dilution 1/65.(Original magnification: 200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47688(KCNN2 Antibody) at dilution 1/65.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47688(KCNN2 Antibody) at dilution 1/65.(Original magnification: 200))
Related Product Information for anti-KCNN2 antibody
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants.
Product Categories/Family for anti-KCNN2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,341 Da
NCBI Official Full Name
small conductance calcium-activated potassium channel protein 2 isoform b
NCBI Official Synonym Full Names
potassium calcium-activated channel subfamily N member 2
NCBI Official Symbol
KCNN2
NCBI Official Synonym Symbols
SK2; hSK2; SKCA2; KCa2.2; SKCa 2
NCBI Protein Information
small conductance calcium-activated potassium channel protein 2
UniProt Protein Name
Small conductance calcium-activated potassium channel protein 2
UniProt Gene Name
KCNN2
UniProt Synonym Gene Names
SK2; SKCa 2; SKCa2

NCBI Description

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Uniprot Description

Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

Research Articles on KCNN2

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Product Notes

The KCNN2 kcnn2 (Catalog #AAA9430670) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNN2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KCNN2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-300. Researchers should empirically determine the suitability of the KCNN2 kcnn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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