Rabbit PI3 Kinase Class III Polyclonal Antibody | anti-PIK3C3 antibody

PI3 Kinase Class III (Phospho-Ser244/249) Antibody

Cat. Num. AAA9429417

• Gene Names: PIK3C3; VPS34; Vps34; hVps34
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
• Synonyms: PI3 Kinase Class III; Polyclonal Antibody; PI3 Kinase Class III (Phospho-Ser244/249) Antibody; hVps34; MGC61518; Phosphatidylinositol 3 kinase catalytic subunit type 3; Phosphatidylinositol 3 kinase class 3; Phosphatidylinositol 3 kinase p100 subunit; Phosphatidylinositol 3-kinase catalytic subunit type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide 3 kinase class 3; Phosphoinositide-3-kinase class 3; PI3 kinase type 3; PI3-kinase type 3; PI3K type 3; Pik3c3; PK3C3_HUMAN; PtdIns 3 kinase type 3; PtdIns-3-kinase type 3; Vps 34; Vps34;; anti-PIK3C3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Phospho-PI3 Kinase Class III (Phospho-Ser244/249) Antibody detects endogenous levels of PI3 Kinase Class III only when phosphorylated at Ser244/249
• Purity/Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0mg/mL (varies by lot)
• Sequence Length: 887

• Applicable Applications for anti-PIK3C3 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: A synthesized peptide derived from human PI3 Kinase Class III around the phosphorylation site of Ser244/249
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of Phospho-PI3 Kinase Class III (Ser244/249) in lysates of 293T?, using Phospho-PI3 Kinase Class III (Ser244/249) Antibody(13265).)

Product Categories/Family for anti-PIK3C3 antibody

Phospho-specific Ab

NCBI and Uniprot Product Information

• NCBI GI #: 34761064
• NCBI GeneID: 5289
• NCBI Accession #: NP_002638.2
• NCBI GenBank Nucleotide #: NM_002647.3
• UniProt Accession #: Q8NEB9; Q15134
• Molecular Weight: 100
• NCBI Official Full Name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1
• NCBI Official Synonym Full Names: phosphatidylinositol 3-kinase catalytic subunit type 3
• NCBI Official Symbol: PIK3C3
• NCBI Official Synonym Symbols: VPS34; Vps34; hVps34
• NCBI Protein Information: phosphatidylinositol 3-kinase catalytic subunit type 3
• UniProt Protein Name: Phosphatidylinositol 3-kinase catalytic subunit type 3
• UniProt Gene Name: PIK3C3
• UniProt Synonym Gene Names: PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3

Uniprot Description

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes ().