Rat Caspase-6 ELISA Kit | Casp6 elisa kit
Rat Caspase-6 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
member of the cysteine-aspartic acid protease (caspase) family that plays a terminal role in apoptosis [RGD, Feb 2006]
Uniprot Description
CASP6: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce. Activation is suppressed by phosphorylation at Ser-257. Belongs to the peptidase C14A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; EC 3.4.22.59; Protease
Chromosomal Location of Human Ortholog: 2q43
Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus
Molecular Function: endopeptidase activity; identical protein binding
Biological Process: acute inflammatory response to non-antigenic stimulus; apoptosis; epithelial cell differentiation; lens development in camera-type eye; positive regulation of apoptosis; positive regulation of neuron apoptosis; positive regulation of retinal cell programmed cell death; proteolysis; response to cytokine stimulus; response to estradiol stimulus; response to gamma radiation; response to glucose stimulus; response to heat; response to hydrogen peroxide; response to iron ion; response to metal ion; response to organic nitrogen; response to organic substance; response to testosterone stimulus
Research Articles on Casp6
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Product Notes
The Rat Casp6 casp6 (Catalog #AAA9428835) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9428835 ELISA Kit recognizes Rat Casp6. It is sometimes possible for the material contained within the vial of "Caspase-6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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