Zinc transporter ZIP1 Recombinant Protein | S39A1 recombinant protein

Recombinant Human Zinc transporter ZIP1 protein

Cat. Num. AAA9422117

• Gene Names: SLC39A1; ZIP1; ZIRTL
• Reactivity: Human
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: Zinc transporter ZIP1; Recombinant Human Zinc transporter ZIP1 protein; Solute carrier family 39 member 1Zinc-iron-regulated transporter-likeZrt- and Irt-like protein 1; ZIP-1; hZIP1; S39A1 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Full lenth of Cytoplasmic Domain, 126-179aa

• Tag Info: His-tag8.4
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for S39A1 recombinant protein

Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.

NCBI and Uniprot Product Information

• NCBI GI #: 430768587
• NCBI GeneID: 27173
• NCBI Accession #: NP_001258886.1
• NCBI GenBank Nucleotide #: NM_001271957.1
• UniProt Accession #: Q9NY26; Q5T4K1; Q8N2H7; Q9BTV0; Q9UBI7; Q9Y2Z7; Q9Y380; B4DDY7
• Molecular Weight: 34kD
• NCBI Official Full Name: zinc transporter ZIP1 isoform a
• NCBI Official Synonym Full Names: solute carrier family 39 member 1
• NCBI Official Symbol: SLC39A1
• NCBI Official Synonym Symbols: ZIP1; ZIRTL
• NCBI Protein Information: zinc transporter ZIP1
• UniProt Protein Name: Zinc transporter ZIP1
• Protein Family: Zinc transporter
• UniProt Gene Name: SLC39A1
• UniProt Synonym Gene Names: IRT1; ZIP1; ZIRTL; ZIP-1; hZIP1

NCBI Description

This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Uniprot Description

SLC39A1: Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells. Belongs to the ZIP transporter (TC 2.A.5) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: membrane; plasma membrane

Molecular Function: inorganic cation transmembrane transporter activity; zinc ion transmembrane transporter activity

Biological Process: cation transport