Phosphoacetylglucosamine mutase Recombinant Protein | AGM1 recombinant protein

Recombinant Human Phosphoacetylglucosamine mutase

Cat. Num. AAA9420534

• Gene Names: PGM3; AGM1; PAGM; IMD23; PGM 3
• Reactivity: Human
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: Phosphoacetylglucosamine mutase; Recombinant Human Phosphoacetylglucosamine mutase; Acetylglucosamine phosphomutase; Curated; AGM1 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Full Length, 1-542aa

• Tag Info: His-SUMO-tag
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for AGM1 recombinant protein

Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

NCBI and Uniprot Product Information

• NCBI GI #: 315707006
• NCBI GeneID: 5238
• NCBI Accession #: NP_001186846.1
• NCBI GenBank Nucleotide #: NM_001199917.1
• UniProt Accession #: O95394; Q5JWR4; Q96J46; Q9H8G5; Q9NS94; Q9NTT6; Q9UFV5; B2RB65; B4DX94; D6RF12; E1P547; E9PF86
• Molecular Weight: 75.8kD
• NCBI Official Full Name: phosphoacetylglucosamine mutase isoform 1
• NCBI Official Synonym Full Names: phosphoglucomutase 3
• NCBI Official Symbol: PGM3
• NCBI Official Synonym Symbols: AGM1; PAGM; IMD23; PGM 3
• NCBI Protein Information: phosphoacetylglucosamine mutase
• UniProt Protein Name: Phosphoacetylglucosamine mutase
• Protein Family: Phosphoacetylglucosamine mutase
• UniProt Gene Name: PGM3
• UniProt Synonym Gene Names: PGM 3

NCBI Description

This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

PGM3: Interconverts GlcNAc-6-P and GlcNAc-1-P. Belongs to the phosphohexose mutase family.

Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 5.4.2.3; Isomerase

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: cytosol

Molecular Function: phosphoacetylglucosamine mutase activity

Biological Process: hemopoiesis; protein amino acid N-linked glycosylation; protein amino acid O-linked glycosylation; UDP-N-acetylglucosamine biosynthetic process

Disease: Immunodeficiency 23