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Western Blot (WB) (Western blot analysis CCNB3 using K562 whole cell lysates)

Rabbit anti-Human CCNB3 Polyclonal Antibody | anti-CCNB3 antibody

CCNB3 Antibody

Reactivity
Human
Applications
Western Blot
Synonyms
CCNB3; Polyclonal Antibody; CCNB3 Antibody; Cyclin B3; G2/mitotic-specific cyclin-B3; CYCB3; anti-CCNB3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
CCNB3 Antibody detects endogenous levels of total CCNB3
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
1395
Applicable Applications for anti-CCNB3 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human CCNB3
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis CCNB3 using K562 whole cell lysates)

Western Blot (WB) (Western blot analysis CCNB3 using K562 whole cell lysates)
Product Categories/Family for anti-CCNB3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,195 Da
NCBI Official Full Name
G2/mitotic-specific cyclin-B3 isoform 3
NCBI Official Synonym Full Names
cyclin B3
NCBI Official Symbol
CCNB3
NCBI Protein Information
G2/mitotic-specific cyclin-B3
UniProt Protein Name
G2/mitotic-specific cyclin-B3
UniProt Gene Name
CCNB3
UniProt Synonym Gene Names
CYCB3
UniProt Entry Name
CCNB3_HUMAN

NCBI Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

CCNB3: Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I. Belongs to the cyclin family. Cyclin AB subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: Xp11

Cellular Component: nucleoplasm

Molecular Function: protein binding

Research Articles on CCNB3

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Product Notes

The CCNB3 ccnb3 (Catalog #AAA9417921) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCNB3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCNB3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the CCNB3 ccnb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCNB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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