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Western Blot (WB) (All lanes: Bone morphogenetic protein 7 antibody at 2ug/ml+mouse kidney tissue)

Rabbit anti-Human Bone morphogenetic protein 7 Polyclonal Antibody | anti-BMP7 antibody

Bone morphogenetic protein 7 Polyclonal Antibody

Gene Names
BMP7; OP-1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Bone morphogenetic protein 7; Polyclonal Antibody; Bone morphogenetic protein 7 Polyclonal Antibody; Osteogenic protein 1; BMP7; OP1; anti-BMP7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Bone morphogenetic protein 7 polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
431
Applicable Applications for anti-BMP7 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Bone morphogenetic protein 7
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(All lanes: Bone morphogenetic protein 7 antibody at 2ug/ml+mouse kidney tissue)

Western Blot (WB) (All lanes: Bone morphogenetic protein 7 antibody at 2ug/ml+mouse kidney tissue)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mousekidney using at dilution of 1:50.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mousekidney using at dilution of 1:50.)
Related Product Information for anti-BMP7 antibody
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Product Categories/Family for anti-BMP7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
655
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,313 Da
NCBI Official Full Name
bone morphogenetic protein 7 preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 7
NCBI Official Symbol
BMP7
NCBI Official Synonym Symbols
OP-1
NCBI Protein Information
bone morphogenetic protein 7
UniProt Protein Name
Bone morphogenetic protein 7
UniProt Gene Name
BMP7
UniProt Synonym Gene Names
OP1; BMP-7; OP-1
UniProt Entry Name
BMP7_HUMAN

Uniprot Description

BMP7: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1. Expressed in the kidney and bladder. Lower levels seen in the brain. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q13

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; protein binding; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cardiac muscle development; dendrite development; epithelial to mesenchymal transition; hindbrain development; inhibition of NF-kappaB transcription factor; mesenchymal cell differentiation; mesonephros development; metanephros development; negative regulation of cell cycle; negative regulation of MAP kinase activity; negative regulation of mitosis; negative regulation of neuron differentiation; negative regulation of NF-kappaB import into nucleus; negative regulation of phosphorylation; negative regulation of transcription, DNA-dependent; neural fold elevation formation; neurite morphogenesis; pharyngeal system development; positive regulation of bone mineralization; positive regulation of heterotypic cell-cell adhesion; positive regulation of osteoblast differentiation; positive regulation of transcription, DNA-dependent; regulation of apoptosis; skeletal development; steroid hormone mediated signaling; ureteric bud development

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Product Notes

The BMP7 bmp7 (Catalog #AAA9415255) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bone morphogenetic protein 7 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Bone morphogenetic protein 7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the BMP7 bmp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bone morphogenetic protein 7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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