Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue using at dilution 1/25.)
Rabbit anti-Human, Mouse NEK1 Polyclonal Antibody | anti-NEK1 antibody
NEK1 Antibody
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue using at dilution 1/25.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue using at dilution 1/25.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/25.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/25.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Uniprot Description
NEK1: a protein kinase related to the NIMA (never in mitosis, gene A) serine/threonine kinase of Aspergillus nidulans. Expressed at high levels during gametogenesis and neurons of the peripheral ganglia. Implicated in the control of meiosis. Mouse mutants lead to facial malformation, male sterility and polycystic kidney disease. Two alternatively spliced human isoforms have been reported.
Protein type: Kinase, protein; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Other group; NEK family
Chromosomal Location of Human Ortholog: 4q33
Cellular Component: centrosome; pericentriolar material; cytoplasm; nucleus
Molecular Function: MAP kinase kinase activity; protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; metal ion binding; ATP binding; protein kinase activity
Biological Process: mitosis; peptidyl-tyrosine phosphorylation; activation of MAPK activity; cell division; MAPKKK cascade; cilium biogenesis; response to ionizing radiation; response to DNA damage stimulus
Disease: Short-rib Thoracic Dysplasia 6 With Or Without Polydactyly
Research Articles on NEK1
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Product Notes
The NEK1 nek1 (Catalog #AAA9414100) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NEK1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NEK1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the NEK1 nek1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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