Rabbit anti-Human, Mouse LEG8 Polyclonal Antibody | anti-LEG8 antibody

LEG8 Antibody

Cat. Num. AAA9411578

• Gene Names: LGALS8; Gal-8; PCTA1; PCTA-1; Po66-CBP
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: LEG8; Polyclonal Antibody; LEG8 Antibody; Galectin-8; Gal-8; Prostate carcinoma tumor antigen 1; PCTA-1; Po66 carbohydrate-binding protein; anti-LEG8 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total LEG8 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 359

• Applicable Applications for anti-LEG8 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:500~1:3000; Immunohistochemistry: 1:50~1:100
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from internal of human LEG8.
• Target Name: LEG8
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from 3T3 cells, using LEG8 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using LEG8 antibody.)

Related Product Information for anti-LEG8 antibody

Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.Su Z.-Z., Proc. Natl. Acad. Sci. U.S.A. 93:7252-7257(1996).Hadari Y.R., Trends Glycosci. Glycotechnol. 9:103-112(1997).Gopalkrishnan R.V., Oncogene 19:4405-4416(2000).

Product Categories/Family for anti-LEG8 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 42544185
• NCBI GeneID: 3964
• NCBI Accession #: NP_006490.3
• NCBI GenBank Nucleotide #: NM_006499.4
• UniProt Accession #: O00214; O15215; Q5T3P5; Q5T3Q4; Q8TEV1; Q96B92; Q9BXC8; Q9H584; Q9H585; Q9UEZ6; Q9UP32; Q9UP33
• Molecular Weight: 40,397 Da
• NCBI Official Full Name: galectin-8 isoform a
• NCBI Official Synonym Full Names: lectin, galactoside-binding, soluble, 8
• NCBI Official Symbol: LGALS8
• NCBI Official Synonym Symbols: Gal-8; PCTA1; PCTA-1; Po66-CBP
• NCBI Protein Information: galectin-8
• UniProt Protein Name: Galectin-8
• UniProt Gene Name: LGALS8
• UniProt Synonym Gene Names: Gal-8; Po66-CBP; PCTA-1
• UniProt Entry Name: LEG8_HUMAN

NCBI Description

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

LGALS8: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: extracellular space; membrane; cytoplasm

Molecular Function: protein binding; carbohydrate binding

Biological Process: plasma cell differentiation; T cell costimulation