Rabbit anti-Human SNX12 Polyclonal Antibody | anti-SNX12 antibody

SNX12 antibody

Cat. Num. AAA9411011

• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: SNX12; Polyclonal Antibody; SNX12 antibody; anti-SNX12 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Sequence Length: 162

• Applicable Applications for anti-SNX12 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500-1:3000; Immunohistochemistry: 1:100-1:250; Immunofluorescence: 1:100-1:200
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 100 and 162 of Human SNX12
• Target Name: SNX12
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample(30 ug of whole cell lysate)A: 293TB: H129915% SDS PAGEPrimary antibody diluted at 1: 1500)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Thyroid Ca, using SNX12 antibody at 1: 100 dilution.)

Immunofluorescence (IF)

(Immunofluorescence analysis of methanol-fixed A431, using SNX12 antibody at 1: 500 dilution.)

Related Product Information for anti-SNX12 antibody

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function. [provided by RefSeq]

Product Categories/Family for anti-SNX12 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 23111030
• NCBI GeneID: 29934
• NCBI Accession #: NP_037478
• NCBI GenBank Nucleotide #: NM_013346.3
• Molecular Weight: 18,342 Da
• NCBI Official Full Name: sorting nexin-12 isoform 1
• NCBI Official Synonym Full Names: sorting nexin 12
• NCBI Official Symbol: SNX12
• NCBI Protein Information: sorting nexin-12
• UniProt Protein Name: Sorting nexin-12
• Protein Family: Sorting nexin
• UniProt Gene Name: SNX12
• UniProt Entry Name: SNX12_HUMAN

NCBI Description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Uniprot Description

SNX12: May be involved in several stages of intracellular trafficking. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: early endosome; extrinsic to membrane

Molecular Function: enzyme binding; phosphoinositide binding; protein binding

Biological Process: endocytosis; negative regulation of protein catabolic process; negative regulation of protein transport; protein transport; regulation of endocytosis; vesicle organization and biogenesis