Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using MBS9410936 at dilution 1/120.)
Rabbit anti-Human LRIG1 Polyclonal Antibody | anti-LRIG1 antibody
LRIG1 Antibody
Gene Names
LRIG1; LIG1; LIG-1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
LRIG1; Polyclonal Antibody; LRIG1 Antibody; LIG1; LIG-1; anti-LRIG1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total LRIG1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
3.8 mg/ml (varies by lot)
Sequence Length
1093
Applicable Applications for anti-LRIG1 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:50-1:200
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the C terminal of human leucine-rich repeats and immunoglobulin-like domains 1
Target Name
LRIG1
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using MBS9410936 at dilution 1/120.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using MBS9410936 at dilution 1/120.)
Related Product Information for anti-LRIG1 antibody
Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family , MET and RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Product Categories/Family for anti-LRIG1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
leucine-rich repeats and immunoglobulin-like domains protein 1
NCBI Official Synonym Full Names
leucine-rich repeats and immunoglobulin-like domains 1
NCBI Official Symbol
LRIG1
NCBI Official Synonym Symbols
LIG1; LIG-1
NCBI Protein Information
leucine-rich repeats and immunoglobulin-like domains protein 1
UniProt Protein Name
Leucine-rich repeats and immunoglobulin-like domains protein 1
Protein Family
UniProt Gene Name
LRIG1
UniProt Synonym Gene Names
LIG1; LIG-1
UniProt Entry Name
LRIG1_HUMAN
Uniprot Description
LRIG1: a singhle-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases. Regulates cadherin-dependent contact inhibition. Interacts with EGFR, HER2, -3, and -4. Two isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, regulatory subunit; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p14
Cellular Component: integral to membrane
Biological Process: sensory perception of sound; otolith morphogenesis
Research Articles on LRIG1
Similar Products
Product Notes
The LRIG1 lrig1 (Catalog #AAA9410936) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRIG1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRIG1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the LRIG1 lrig1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRIG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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