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Western Blot (WB) (Western blot analysis of extracts from rat brain cells, using NudC (Ab-326) antibody.)

Rabbit NudC Polyclonal Antibody | anti-NudC antibody

NudC (Ab-326) Antibody

Gene Names
NUDC; HNUDC; MNUDC; NPD011
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
NudC; Polyclonal Antibody; NudC (Ab-326) Antibody; MNUDC protein; Nuclear distribution gene C (A.nidulans) homolog; SIG-92; anti-NudC antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total NudC protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
331
Applicable Applications for anti-NudC antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized non-phosphopeptide derived from human NudC around the phosphorylation site of serine 326 (D-F-S(p)-K-A).
Target Name
NudC
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from rat brain cells, using NudC (Ab-326) antibody.)

Western Blot (WB) (Western blot analysis of extracts from rat brain cells, using NudC (Ab-326) antibody.)

Western Blot (WB)

(Western blot analysis of extracts from A549 cells and HepG2(Lane 3) cells, using NudC (Ab-326) antiobdy. The lane on the left is treated with systhesized peptide.)

Western Blot (WB) (Western blot analysis of extracts from A549 cells and HepG2(Lane 3) cells, using NudC (Ab-326) antiobdy. The lane on the left is treated with systhesized peptide.)
Related Product Information for anti-NudC antibody
Plays a role in neurogenesis and neuronal migration By similarity. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
Product Categories/Family for anti-NudC antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,243 Da
NCBI Official Full Name
nuclear migration protein nudC
NCBI Official Synonym Full Names
nudC nuclear distribution protein
NCBI Official Symbol
NUDC
NCBI Official Synonym Symbols
HNUDC; MNUDC; NPD011
NCBI Protein Information
nuclear migration protein nudC
UniProt Protein Name
Nuclear migration protein nudC
Protein Family
UniProt Gene Name
NUDC
UniProt Entry Name
NUDC_HUMAN

NCBI Description

This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]

Uniprot Description

NUDC: a cytoskeletal protein that is a component of the dynactin complex. The cytoplasmic dynein/dynactin complex, a minus-end-directed motor, powers various) aspects of mitosis, including establishment of bipolarity, organization of spindle poles, alignment and segregation of chromosomes, as well as regulation of microtubule dynamics. Phosphorylation by PLK1 may play a critical role in cytokinesis.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: nucleoplasm; microtubule; cytoplasm; cytosol

Molecular Function: protein binding

Biological Process: cell proliferation; mitosis; cell division; multicellular organismal development; mitotic cell cycle

Research Articles on NudC

Similar Products

Product Notes

The NudC nudc (Catalog #AAA9409192) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NudC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the NudC nudc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NudC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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