Rabbit anti-Human FAR2 Polyclonal Antibody | anti-FAR2 antibody

FAR2 Antibody

Cat. Num. AAA9404949

• Gene Names: FAR2; MLSTD1; SDR10E2
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: FAR2; Polyclonal Antibody; FAR2 Antibody; MLSTD1; SDR10E2; anti-FAR2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total FAR2 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2.2 mg/ml (varies by lot)
• Sequence Length: 515

• Applicable Applications for anti-FAR2 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:1000-1:5000; Immunohistochemistry: 1:50-1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human fatty acyl CoA reductase 2
• Target Name: FAR2
• Preparation and Storage: Store at -20 degree C

Testing Data

(Gel: 6%SDS-PAGE Lysates (from left to right): Human fetal liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/1000 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/50.)

Related Product Information for anti-FAR2 antibody

This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22.

Product Categories/Family for anti-FAR2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 422398861
• NCBI GeneID: 55711
• NCBI Accession #: NP_001258712.1
• NCBI GenBank Nucleotide #: NM_001271783.1
• UniProt Accession #: Q96K12; Q9H0D5; Q9NVW8; F8VV73
• Molecular Weight: 48,537 Da
• NCBI Official Full Name: fatty acyl-CoA reductase 2 isoform 1
• NCBI Official Synonym Full Names: fatty acyl CoA reductase 2
• NCBI Official Symbol: FAR2
• NCBI Official Synonym Symbols: MLSTD1; SDR10E2
• NCBI Protein Information: fatty acyl-CoA reductase 2
• UniProt Protein Name: Fatty acyl-CoA reductase 2
• Protein Family: Fatty acyl-CoA reductase
• UniProt Gene Name: FAR2
• UniProt Synonym Gene Names: MLSTD1
• UniProt Entry Name: FACR2_HUMAN

NCBI Description

This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012]

Uniprot Description

MLSTD1: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. Belongs to the fatty acyl-CoA reductase family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 1.2.1.n2; Oxidoreductase

Chromosomal Location of Human Ortholog: 12p11.22

Cellular Component: peroxisomal membrane; peroxisomal matrix; endoplasmic reticulum membrane; integral to membrane; peroxisome

Molecular Function: long-chain-fatty-acyl-CoA reductase activity

Biological Process: cellular lipid metabolic process; ether lipid biosynthetic process