Rabbit anti-Human IL13RA1 Polyclonal Antibody | anti-IL13RA1 antibody

IL13RA1 antibody

Cat. Num. AAA9403706

• Gene Names: IL13RA1; NR4; CT19; CD213A1; IL-13Ra
• Reactivity: Human
• Applications: Western Blot
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: IL13RA1; Polyclonal Antibody; IL13RA1 antibody; NR4; CD213A1; IL-13Ra; anti-IL13RA1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total IL13RA1 antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 427

• Applicable Applications for anti-IL13RA1 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500 - 1:2000
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human IL13RA1.
• Target Name: IL13RA1
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using IL13RA1 antibody.)

Related Product Information for anti-IL13RA1 antibody

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Product Categories/Family for anti-IL13RA1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 4504647
• NCBI GeneID: 3597
• NCBI Accession #: NP_001551.1
• NCBI GenBank Nucleotide #: NM_001560.2
• UniProt Accession #: P78552; O95646; Q5JSL4; Q99656; Q9UDY5
• Molecular Weight: 31,659 Da
• NCBI Official Full Name: interleukin-13 receptor subunit alpha-1
• NCBI Official Synonym Full Names: interleukin 13 receptor, alpha 1
• NCBI Official Symbol: IL13RA1
• NCBI Official Synonym Symbols: NR4; CT19; CD213A1; IL-13Ra
• NCBI Protein Information: interleukin-13 receptor subunit alpha-1
• UniProt Protein Name: Interleukin-13 receptor subunit alpha-1
• Protein Family: Interleukin-13 receptor
• UniProt Gene Name: IL13RA1
• UniProt Synonym Gene Names: IL13R; IL13RA; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19
• UniProt Entry Name: I13R1_HUMAN

NCBI Description

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

Uniprot Description

IL13R: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. Belongs to the type I cytokine receptor family. Type 5 subfamily.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: interleukin-13 receptor complex; plasma membrane

Molecular Function: protein binding; interleukin-13 receptor activity

Biological Process: positive regulation of immunoglobulin production; cell surface receptor linked signal transduction; positive regulation of B cell proliferation