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Testing Data (1:1000 dilution of this antibody detected CHD3 on 40ug of cell lysates)

Mouse TFIIH Monoclonal Antibody | anti-TFIIH antibody

TFIIH(N-term) Monoclonal Antibody

Gene Names
GTF2H1; P62; BTF2; TFB1; TFIIH
Reactivity
Human, Mouse, Dog, Porcine, Rat
Applications
Western Blot, Immunocytochemistry
Purity
Purified by antigen-affinity chromatography.
Synonyms
TFIIH; Monoclonal Antibody; TFIIH(N-term) Monoclonal Antibody; general transcription factor IIH subunit 1 BTF2 p62 basic transcription factor 2 62 kDa subunit general transcription factor IIH polypeptide 1 TFIIH basal transcription factor complex p62 subunit; anti-TFIIH antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Dog, Porcine, Rat
Clonality
Monoclonal
Isotype
IgG1
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Sequence Length
548
Applicable Applications for anti-TFIIH antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
Western blotting: 1:1000
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant fragment, corresponding to amino acids 1aa-279aa of human GTF2H1 (N-terminus).
Target Name
TFIIH
Preparation and Storage
store at -20 degree C

Testing Data

(1:1000 dilution of this antibody detected CHD3 on 40ug of cell lysates)

Testing Data (1:1000 dilution of this antibody detected CHD3 on 40ug of cell lysates)
Product Categories/Family for anti-TFIIH antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,738 Da
NCBI Official Full Name
general transcription factor IIH subunit 1
NCBI Official Synonym Full Names
general transcription factor IIH, polypeptide 1, 62kDa
NCBI Official Symbol
GTF2H1
NCBI Official Synonym Symbols
P62; BTF2; TFB1; TFIIH
NCBI Protein Information
general transcription factor IIH subunit 1
UniProt Protein Name
General transcription factor IIH subunit 1
UniProt Gene Name
GTF2H1
UniProt Synonym Gene Names
BTF2; BTF2 p62
UniProt Entry Name
TF2H1_HUMAN

Uniprot Description

GTF2H1: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 11p15.1-p14

Cellular Component: nucleoplasm; holo TFIIH complex

Molecular Function: RNA polymerase subunit kinase activity; DNA-dependent ATPase activity; protein binding; protein kinase activity

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; DNA repair; termination of RNA polymerase I transcription; protein amino acid phosphorylation; regulation of gene expression, epigenetic; mRNA capping; negative regulation of gene expression, epigenetic; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; RNA elongation from RNA polymerase II promoter; nucleotide-excision repair, DNA damage removal; positive regulation of transcription from RNA polymerase II promoter; gene expression; regulation of cyclin-dependent protein kinase activity; transcription initiation from RNA polymerase I promoter

Research Articles on TFIIH

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Product Notes

The TFIIH gtf2h1 (Catalog #AAA9400062) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TFIIH(N-term) Monoclonal Antibody reacts with Human, Mouse, Dog, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TFIIH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Western blotting: 1:1000. Researchers should empirically determine the suitability of the TFIIH gtf2h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TFIIH, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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