Pigeon Hypoxia Inducible Factor 2 Alpha (HIF2A) ELISA Kit | HIF2A elisa kit

Pigeon Hypoxia Inducible Factor 2 Alpha (HIF2A) ELISA Kit

• Gene Names: Epas1; HLF; Hif2a
• Reactivity: Pigeon
• Synonyms: Hypoxia Inducible Factor 2 Alpha (HIF2A); Pigeon Hypoxia Inducible Factor 2 Alpha (HIF2A) ELISA Kit; HIF2A elisa kit

• Reactivity: Pigeon

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 8953577
• NCBI GeneID: 29452
• UniProt Accession #: Q9JHS1
• Molecular Weight: 96,718 Da
• NCBI Official Full Name: hypoxia inducible factor 2 alpha
• NCBI Official Synonym Full Names: endothelial PAS domain protein 1
• NCBI Official Symbol: Epas1
• NCBI Official Synonym Symbols: HLF; Hif2a
• NCBI Protein Information: endothelial PAS domain-containing protein 1
• UniProt Protein Name: Endothelial PAS domain-containing protein 1
• UniProt Gene Name: Epas1
• UniProt Synonym Gene Names: Hif2a; EPAS-1; HIF-2-alpha; HIF2-alpha
• UniProt Entry Name: EPAS1_RAT

NCBI Description

activates luciferase activity after transfection [RGD, Feb 2006]

Uniprot Description

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD ().