Hamster Solute Carrier Family 22 Member 5 (SLC22A5) ELISA Kit | SLC22A5 elisa kit
Hamster Solute Carrier Family 22 Member 5 (SLC22A5) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
mediates high-affinity sodium-dependent carnitine transport and sodium-independent organic cation transport [RGD, Feb 2006]
Uniprot Description
SLC22A5: Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3. Defects in SLC22A5 are the cause of systemic primary carnitine deficiency (CDSP). CDSP is an autosomal recessive disorder of fatty acid oxidation caused by defective carnitine transport. Present early in life with hypoketotic hypoglycemia and acute metabolic decompensation, or later in life with skeletal myopathy or cardiomyopathy. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass
Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border membrane; integral to membrane; integral to plasma membrane; mitochondrion
Molecular Function: antibiotic transporter activity; ATP binding; carnitine transporter activity; cation:cation antiporter activity; PDZ domain binding; protein binding; quaternary ammonium group transmembrane transporter activity; symporter activity; transmembrane transporter activity
Biological Process: adult heart development; antibiotic transport; carnitine metabolic process; carnitine transport; locomotory behavior; mitochondrion organization and biogenesis; quaternary ammonium group transport; quorum sensing during interaction with host; reproductive structure development; sodium ion transport; transmembrane transport; triacylglycerol metabolic process
Research Articles on SLC22A5
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Product Notes
The Hamster SLC22A5 slc22a5 (Catalog #AAA9361794) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9361794 ELISA Kit recognizes Hamster SLC22A5. It is sometimes possible for the material contained within the vial of "Solute Carrier Family 22 Member 5 (SLC22A5), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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