Hamster Grancalcin (GCA) ELISA Kit | GCA elisa kit
Hamster Grancalcin (GCA) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq, Jul 2008]
Uniprot Description
GCA: Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 2q24.2
Cellular Component: cytoplasm; plasma membrane
Molecular Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: proteolysis
Research Articles on GCA
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Product Notes
The Hamster GCA gca (Catalog #AAA9359821) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9359821 ELISA Kit recognizes Hamster GCA. It is sometimes possible for the material contained within the vial of "Grancalcin (GCA), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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