Hamster Metastasis-Associated Protein MTA1 (MTA1) ELISA Kit | MTA1 elisa kit
Hamster Metastasis-Associated Protein MTA1 (MTA1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
high expression of this protein correlates with the metastatic potential of cells; may have a role in gene regulation [RGD, Feb 2006]
Uniprot Description
MTA1: metastasis-associated protein. A component of the NuRD ATP-dependent chromatin remodeling and histone deacetylase complex. Interacts with HDAC1. Expressed at high levels in metastatic cells. Two alternatively spliced isoforms have been described. The long isoform is a co-repressor of estrogen receptor (ER). The short isoform binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
Protein type: Nuclear receptor co-regulator; Motility/polarity/chemotaxis; Transcription, coactivator/corepressor
Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; endoplasmic reticulum; Golgi apparatus; intracellular membrane-bound organelle; microtubule; nuclear envelope; nucleoplasm; nucleus; NuRD complex; rough endoplasmic reticulum
Molecular Function: chromatin binding; enzyme binding; protein binding; sequence-specific DNA binding; transcription coactivator activity; transcription corepressor activity; transcription factor activity; zinc ion binding
Biological Process: circadian regulation of gene expression; double-strand break repair; entrainment of circadian clock by photoperiod; female pregnancy; locomotor rhythm; proteasomal ubiquitin-dependent protein catabolic process; regulation of gene expression, epigenetic; regulation of inflammatory response; regulation of transcription, DNA-dependent; response to ionizing radiation; response to lipopolysaccharide; secretory granule organization and biogenesis; transcription, DNA-dependent
Research Articles on MTA1
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Product Notes
The Hamster MTA1 mta1 (Catalog #AAA9358278) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9358278 ELISA Kit recognizes Hamster MTA1. It is sometimes possible for the material contained within the vial of "Metastasis-Associated Protein MTA1 (MTA1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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