Sheep Phosphatidate Cytidylyltransferase 2 (PCDS2) ELISA Kit | PCDS2 elisa kit

Sheep Phosphatidate Cytidylyltransferase 2 (PCDS2) ELISA Kit

Cat. Num. AAA9357427

• Reactivity: Sheep
• Synonyms: Phosphatidate Cytidylyltransferase 2 (PCDS2); Sheep Phosphatidate Cytidylyltransferase 2 (PCDS2) ELISA Kit; PCDS2 elisa kit

• Reactivity: Sheep

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 20143480
• NCBI GeneID: 8760
• NCBI Accession #: NP_003809.1
• NCBI GenBank Nucleotide #: NM_003818.3
• Molecular Weight: 29,890 Da
• NCBI Official Full Name: phosphatidate cytidylyltransferase 2
• NCBI Official Synonym Full Names: CDP-diacylglycerol synthase 2
• NCBI Official Symbol: CDS2
• NCBI Protein Information: phosphatidate cytidylyltransferase 2
• UniProt Protein Name: Phosphatidate cytidylyltransferase 2
• UniProt Gene Name: CDS2
• UniProt Synonym Gene Names: CDS 2
• UniProt Entry Name: CDS2_HUMAN

NCBI Description

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]

Uniprot Description

CDS2: Provides CDP-diacylglycerol an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. Belongs to the CDS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Endoplasmic reticulum; Lipid Metabolism - glycerophospholipid; EC 2.7.7.41; Transferase; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: endoplasmic reticulum membrane; integral to membrane; membrane; mitochondrial inner membrane

Molecular Function: phosphatidate cytidylyltransferase activity

Biological Process: CDP-diacylglycerol biosynthetic process; glycerophospholipid biosynthetic process; phosphatidylglycerol biosynthetic process; phospholipid metabolic process