Mouse CDC14 cell division cycle 14 homolog B (S. cerevisiae) ELISA Kit | CDC14B elisa kit
Mouse Dual specificity protein phosphatase CDC14B, CDC14B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
CDC14B: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases. Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.48; EC 3.1.3.16; Protein phosphatase, dual-specificity; Motility/polarity/chemotaxis; Nucleolus
Cellular Component: nucleoplasm; nuclear membrane; nucleolus; nucleus
Molecular Function: hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; phosphoric monoester hydrolase activity; protein tyrosine phosphatase activity; protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity
Biological Process: dephosphorylation; anaphase-promoting complex activation; protein amino acid dephosphorylation; G2/M transition DNA damage checkpoint; DNA repair; response to DNA damage stimulus
Research Articles on CDC14B
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Product Notes
The Mouse CDC14B cdc14b (Catalog #AAA9342681) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342681 ELISA Kit recognizes Mouse CDC14B. It is sometimes possible for the material contained within the vial of "CDC14 cell division cycle 14 homolog B (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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