Mouse mitogen-activated protein kinase-activated protein kinase 2 ELISA Kit | MAPKAPK2 elisa kit
Mouse MAP kinase-activated protein kinase 2, MAPKAPK2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MAPKAPK2: a member of the MAPKAPK family of protein kinases. It is phosphorylated and activated by p38 in response to cytokines, stress and chemotactic factors.MAPKAPK-2 is apparently a direct target of p38 MAPK. HSP27 is one of its in vivo substrates. Two transcript variants encoding two different isoforms have been described.
Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); CAMK group; MAPKAPK family; MAPKAPK subfamily
Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleus
Molecular Function: calmodulin-dependent protein kinase activity; nucleotide binding; protein kinase activity; transferase activity; calmodulin binding; protein serine/threonine kinase activity; protein binding; signal transducer activity; calcium-dependent protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups; mitogen-activated protein kinase binding; kinase activity; ATP binding
Biological Process: positive regulation of tumor necrosis factor biosynthetic process; protein amino acid autophosphorylation; cellular response to stress; mRNA stabilization; MAPKKK cascade; response to lipopolysaccharide; protein amino acid phosphorylation; peptidyl-serine phosphorylation; response to cytokine stimulus; regulation of interleukin-6 production; toll-like receptor signaling pathway; response to stress; regulation of tumor necrosis factor production; G2/M transition DNA damage checkpoint; inflammatory response; vascular endothelial growth factor receptor signaling pathway; inner ear development; response to DNA damage stimulus; phosphorylation
Research Articles on MAPKAPK2
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Product Notes
The Mouse MAPKAPK2 mapkapk2 (Catalog #AAA9341712) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341712 ELISA Kit recognizes Mouse MAPKAPK2. It is sometimes possible for the material contained within the vial of "mitogen-activated protein kinase-activated protein kinase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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